Market Isosorbide Mononitrate in HK and China 2005.03.29

(Hong Kong, 29 March 2005) - Lee's Pharmaceutical Holdings Limited (GEM) Stock: 8221; Website: announced today that the Group has signed a Supply and Distribution Agreement with Marvecs Services S.r.l. for the distribution and marketing of Vasdilat® slow-released capsules (Isosorbide Mononitrate), throughout Hong Kong and the People's Republic of China.

Vasdilat®~Isosorbide Mononitrate (ISMN), is a type of vasodilator with effects on both arteries and veins. The pain of coronary heart disease (angina) usually occurs when the heart requires more blood and oxygen than its blood vessels supplying the heart can deliver. Our ISMN capsule contains 30mg of isosorbide mononitrate in a slow-released formulation for oral administration, is indicated for the prevention and long-term treatment of angina pectoris associated with coronary artery disease. ISMN relaxes blood vessels, increasing the blood and oxygen supply to the heart. It reduces the pressure that the heart has to pump against and hence the Heart's work and need for oxygen, and also increases supply of oxygen to the heart by dilating the arteries which supply the heart itself. Isosorbide mononitrate is in the class of drugs called anti-anginal medications….

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